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. Author manuscript; available in PMC: 2019 May 31.
Published in final edited form as: Neurotox Res. 2018 Oct 17;35(2):421–431. doi: 10.1007/s12640-018-9968-1

Figure 4.

Figure 4.

Effects of LPS and ROT on the expression of circadian clock core genes and proteins. Rats were given LPS (5 mg/kg, i.p. x1), and 7 months later 20 injections of rotenone (0.5 mg/kg, s.c., 5 time/week for 4 weeks). Two weeks after the last ROT treatment, rats were sacrificed and cortex was collected for analysis. A, mRNA expression of circadian clock core genes; B, The expression of BMAL1 protein; C, The expression of CLOCK protein. Values were mean ± SEM (n = 6–9).

*Significantly different from the control group,

#Significantly different from the LPS group, p<0.05.