Table 3.

MRS measures as a function of patient subgroups

MRS metabolite	un-medicated OCD (n = 5)	refractory OCD (n = 18)	t(df)	p	severe OCD (n = 16)	moderate OCD (n = 7)	t(df)	p
GABA+	2.43 ± 0.23	2.40 ± 0.66	0.093 (21)	0.927	2.37 ± 0.61	2.48 ± 0.58	0.404 (21)	0.69
Glx	1.93 ± 0.42	2.15 ± 0.51	0.903 (21)	0.377	2.12 ± 0.56	2.06 ± 0.32	0.258 (21)	0.80
GABA+/Glx Ratio	1.31 ± 0.34	1.15 ± 0.29	1.116 (21)	0.277	1.16 ± 0.30	1.22 ± 0.32	0.436 (21)	0.667

ACC anterior cingulate cortex, GABA gamma-aminobutyric acid, Glx glutamate-glutamine, HC healthy control, MRS magnetic resonance spectroscopy, OCD obsessive-compulsive disorder