Fig. 6.

Correlation between Kaplan-Meier survival plots of the clinical outcomes and mRNA co-overexpression of indicated luminal SeCEP genes based on TCGA (a, c, e) and METABRIC (b, d, f) patient data. “N” refers to “Number of patients,” and “NE” refers to “Number of Events (Overall Survival status = DECEASED)”. Each plot shows the log-rank p-value and Hazard Ratio (HR) with 95% Confidence Interval (CI) between the two groups. The red line designates the patient subpopulation showing statistically significant overexpression of the indicated luminal-specific genes (“altered”). The blue line designates the group of patients not showing statistically significant overexpression of the indicated luminal-specific genes (“not altered”). Overexpression of CLEC3A provides less prognostic value than overexpression of CLEC3A in combination with other secreted factors