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. 2019 May 30;20:310. doi: 10.1186/s13063-019-3446-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Standard Protocol Items: Recommendations for Interventional Trials Statement (SPIRIT). Overview of study process and outcome assessment. BDI-II, Beck Depression Inventory-II; CDR, Clinical Dementia Rating; d, day; DSST, Digit Symbol Substitution Test; DST, Digit Span Test; GDS, Global Deterioration Scale; MoCA-K, Korean version of Montreal Cognitive Assessment; MRI, magnetic resonance imaging; SNSB-II, Seoul Neuropsychological Screening Battery-II; STAI, State-Trait Anxiety Inventory; wk., week; F/U, follow up