Table 2.

The items from the World Health Organization Trial Registration Data Set

Data category	Information
Primary registry and trial identifying number	CRIS KCT0002896
Date of registration in primary registry	25 May 2018
Sponsor	KIOM
Contact for public/scientific queries	JHL, KMD, Ph.D (omdjun@kiom.re.kr)
Public title	None
Scientific title	Neurocircuitry of Acupuncture Effect on Cognitive Improvement in Patients with Mild Cognitive Impairment Using Magnetic Resonance Imaging: A Study Protocol for a Randomized Controlled Trial
Countries of recruitment	Republic of Korea
Health condition(s) or problem(s) studied	MCI
Intervention(s)	Active comparator: acupuncture
	Sham comparator: non-penetrating sham acupuncture
Key inclusion and exclusion criteria	Ages eligible for study: 50–70 years; sexes eligible for study: both; accepts healthy volunteers: no
	Inclusion criteria: diagnosis of MCI, MoCA-K < 23, CDR score of 0.5, GDS grade 2–3
	Exclusion criteria: diagnosis of dementia, neurological disorders, mental disorders
Study type	Interventional
	Allocation: randomized; intervention model: parallel assignment; blinding: subject-assessor blinding
	Primary purpose: treatment
Date of first enrolment	18 July 2018
Target sample size	50
Recruitment status	Recruiting
Primary outcome(s)	DST
Key secondary outcomes	DSST, MoCA-K

CRIS Clinical Research Information Service, DSST Digit Symbol Substitution Test, DST Digit Span Test, MCI mild cognitive impairment, MoCA-K Korean version of Montreal Cognitive Assessment, KIOM Korean Institute of Oriental Medicine