Table 1.
Longitudinal Population-based Studies of Occupational Risk for Asthma
| First Author, Year, Location (Reference) | Study Type | Incident Cases (n [Total Population]) | Definition of Exposure | PAF (%) |
|---|---|---|---|---|
| Katz, 1999, Israel (30) | Population follow-up ages 18–21 yr at baseline | 588 (59,058) | Military exposure combat or maintenance vs. clerical | 44 |
| Karjalainen, 2001, Finland (31) | Population follow-up ages 25–59 yr at baseline | 49,575 (1,852,848) | Work-related compensation | 22 |
| Eagan, 2002, Norway (25) | Population follow-up ages 15–70 yr at baseline | 101 (2,723) | Self-reported dust and fume exposure at baseline | 14 |
| LeVan, 2006, Singapore (27) | Population follow-up ages 13–44 yr at baseline | 1,426 (52,325) | Occupations exposed to dust, smoke, or vapors | 8.6 |
| Kogevinas, 2007, international (32) | Population follow-up ages 20–44 yr at baseline | 133 (6,837) | Exposure to high-risk substances by JEM | 11 |
| Hedlund, 2006, Sweden (33) | Population follow-up ages 36–37, 50–52, and 66–67 yr at baseline | 271 (5,933) | Blue collar industrial workers vs. others | 9 |
| Lillienberg, 2013, international (28) | Population follow-up in RHINE population ages 20–44 yr at baseline | 129 males (5,933) | Exposure to high-risk substances by JEM | 14 |
| 286 females (6,253) | 7 | |||
| Hoy, 2013, Australia (Tasmania) (26) | Population follow-up ages 13–44 yr at baseline | 290 (792*) | Exposure to high-risk substances by JEM | 10 |
| Ghosh, 2013, UK (29) | Population follow-up of birth cohort up to age 42 yr | 611 (7,088†) | Any asthma JEM >0 | 16.3 |
Definition of abbreviations: JEM = job exposure matrix; PAF = population attributable fraction; RHINE = Respiratory Health in Northern Europe; UK = United Kingdom.
The pooled estimated PAF for the occupational contribution to incident asthma was 16% (95% confidence interval, 10–22%).
*
Subjects with asthma at baseline excluded.
†
Total before subjects with childhood asthma were excluded.