Table 1.

Main results of two recent meta-analyses on pregnancy rates after FSH treatment of men with idiopathic infertility.

Inclusion criterion	Number of patients treated with FSH*	Number of patients treated with placebo or untreated	Odds ratio [95% confidence interval] for spontaneous pregnancy rate#	Reference of the meta-analysis
Randomized controlled clinical trials	201	211	4.94 [2.13–11.44]	(39)
Controlled clinical trials	384	308	4.50 [2.17–9.33]	(40)

^*In one clinical trial included in each meta-analysis (n = 19 patients in verum and n = 20 patients in control group) hMG + hCG injections were given instead of purified or recombinant FSH.

^#Test for overall effect: Z = 3.72 (P = 0.00020) (39) and Z = 4.04 (P < 0.0001) (40).