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. 2019 May 24;10:1084. doi: 10.3389/fimmu.2019.01084

Table 1.

Macrophage transcriptomes overview.

Original Manuscript Jablonski et al. (25) Buscher et al. (22)
Macrophages Bone marrow-derived, BMDM Peritoneal macrophages
Activation LPS (100 ng/mL) +IFN-γ (20 ng/mL), 24 h for Classically activated; LPS (2 ng/mL) for 4 h
IL-4 (20 ng/mL), 24 h for Alternatively activated.
Transcriptome Affymetrix, GSE69607 Affymetrix, GSE38705 Orozco et al. (21)
LPS source Sigma-Aldrich L2880 List Biological Inc., Campbell, CA
Gene lists DE between classically activated vs. alternatively activated, filtered for unique genes. Positively [M1(=LPS+)] or negatively [M2(=LPS–)] correlated with IL-12/arginase-1