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Plasma concentrations of selected tamoxifen metabolites stratified according to CYP2D6 genotype in 117 Iranian breast cancer patients receiving 20 mg/day tamoxifen for at least 4 months. Non-adherent patients with plasma tamoxifen concentrations <100 nM were excluded. The patients who were scheduled for the dose escalation trial are depicted in red. The differences between the genotype groups were assessed by Kruskal–Wallis Test.
