Table 1.
The main characteristics of the patients.
| Characteristics | All patients enrolled Number of patients (%) N = 134 (100) | Patients receiving 20 mg/day Number of patients (%) N = 117 (100) | Patients receiving 30 or 40 mg/day Number of patients (%) N = 17 (100) |
|---|---|---|---|
| Age (years) | |||
| Median | 45 | 45 | 46 |
| Range | 28–71 | 28–71 | 34–68 |
| BMI | |||
| Median | 22 | 22 | 23 |
| Range | 18–32 | 18–32 | 19.5–30 |
| Menopausal status | |||
| Premenopausal | 60 (44.8) | 57 (48.7) | 3 (17.7) |
| Postmenopausal | 70 (52.2) | 56 (47.9) | 14 (82.3) |
| Unknown | 4 (3.0) | 4 (3.4) | 0 (0.0) |
| Chemotherapy | |||
| Yes | 116 (86.6) | 100 (85.5) | 16 (94.1) |
| No | 15 (11.2) | 14 (12.0) | 1 (5.9) |
| Unknown | 3 (2.2) | 3 (2.5) | 0 (0.0) |
| Radiation | |||
| Yes | 122 (91.1) | 105 (89.7) | 17 (100) |
| No | 9 (6.7) | 9 (7.7) | 0 (0.0) |
| Unknown | 3 (2.2) | 3 (2.6) | 0 (0.0) |
| Duration of tamoxifen use | |||
| >4 months, ≤2 years | 81 (60.4) | 71 (60.7) | 10 (58.8) |
| >2 years | 53 (39.6) | 46 (39.3) | 7 (41.2) |
| Tumor size (cm) | |||
| ≤2 | 33 (24.6) | 31 (26.5) | 2 (11.8) |
| 2.1–5 | 67 (50.0) | 57 (48.7) | 10 (58.8) |
| >5 | 11 (8.2) | 9 (7.7) | 2 (11.8) |
| Unknown | 23 (17.2) | 20 (17.1) | 3 (17.6) |
| Grading | |||
| G1 | 16 (11.9) | 15 (12.8) | 1 (5.9) |
| G2 | 62 (46.3) | 54 (46.2) | 8 (47.1) |
| G3 | 32 (23.9) | 31 (26.5) | 1 (5.9) |
| Unknown | 24 (17.9) | 17 (14.5) | 7 (41.2) |
| Nodal status | |||
| Negative | 51 (38.0) | 42 (35.9) | 9 (52.9) |
| Positive | 62 (46.3) | 56 (47.9) | 6 (35.3) |
| Unknown | 21 (15.7) | 19 (16.2) | 2 (11.8) |
| Estrogen receptor status | |||
| Positive | 127 (94.8) | 111 (94.9) | 16 (94.1) |
| Negative | 2 (1.5) | 2 (1.7) | 0 (0.0) |
| Unknown | 5 (3.7) | 4 (3.4) | 1 (5.9) |
| Progesterone receptor status | |||
| Positive | 121 (90.3) | 105 (89.8) | 16 (94.1) |
| Negative | 6 (4.5) | 6 (5.1) | 0 (0.0) |
| Unknown | 7 (5.2) | 6 (5.1) | 1 (5.9) |
| HER-2 status | |||
| Positive | 16 (11.9) | 14 (12.0) | 2 (11.8) |
| Negative | 106 (79.1) | 94 (80.3) | 12 (70.6) |
| Unknown | 12 (9.0) | 9 (7.7) | 3 (17.6) |
BMI, Body mass index; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.