Table 1.
RIFLE SCr criterion | AKIN SCr criterion | KDIGO SCr crtiterion | RIFLE/AKIN/KDIGO Urine output criterion | |||
---|---|---|---|---|---|---|
Risk | ≥1.5-fold increase from baseline SCr or decrease in GFR ≥25% | Stage 1 | ≥0.3 mg/dL increase or ≥1.5-fold increase from baseline SCr within 48 hrs | Stage 1 | ≥0.3 mg/dL increase within 48 hrs or 1.5–1.9 times the baseline within 7 days | <0.5 mL/kg/h for >6 hrs |
Injury | ≥2-fold increase from baseline SCr or decrease in GFR ≥50% | Stage 2 | ≥2-fold increase from baseline SCr | Stage 2 | 2.0–2.9 times the baseline within 7 days | <0.5 mL/kg/h for ≥12 hrs |
Failure | ≥3-fold increase from baseline SCr or increase to ≥4.0 mg/dL or decrease in GFR ≥75% | Stage 3 | ≥3-fold increase from baseline SCr or increase to ≥4.0 mg/dL with an acute increase of >0.5 mg/dL or initiation of RRT | Stage 3 | ≥3 times the baseline within 7 days or increase to ≥4.0 mg/dL with an acute increase of >0.5 mg/dL or initiation of RRT | <0.3 mL/kg/h for ≥24 hrs or anuria for ≥12 hrs |
Loss | Persistent renal failure >4 weeks | – | – | – | ||
ESRD | Persistent renal failure >3 months | – | – | – |
SCr – serum creatinine; GFR – glomerular filtration rate; RRT – renal replacement therapy.