Summary of findings 2. Buried (subcutaneous) versus non‐buried catheter for preventing catheter‐related infections in chronic peritoneal dialysis patients.
| Buried (subcutaneous) versus non‐buried catheter for preventing catheter‐related infections in chronic peritoneal dialysis patients | |||||
| Patient or population: chronic peritoneal dialysis patients Intervention: buried (subcutaneous) catheter Comparison: non‐buried catheter | |||||
| Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | No. of participants or patient‐months (studies) | Certainty of the evidence (GRADE) | |
| Risk with non‐buried | Risk with buried (subcutaneous) | ||||
| Peritonitis rate (patient‐months) | 37 per 1,000 | 43 per 1,000 (14 to 133) | RR 1.16 (0.37 to 3.60) | 2511 (2) | ⊕⊝⊝⊝ VERY LOW 1 |
| Exit‐site/tunnel infection rate (patient‐months) | 31 per 1,000 | 36 per 1,000 (12 to 106) | RR 1.15 (0.39 to 3.42) | 2511 (2) | ⊕⊝⊝⊝ VERY LOW 1 |
| Technique failure | 367 per 1,000 | 268 per 1,000 (125 to 568) | RR 0.73 (0.34 to 1.55) | 60 (1) | ⊕⊝⊝⊝ VERY LOW 2 |
| Death (all causes) | 169 per 1,000 | 153 per 1,000 (66 to 353) | RR 0.90 (0.39 to 2.08) | 119 (2) | ⊕⊕⊕⊝ MODERATE 3 |
| *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio | |||||
| GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect | |||||
1 Downgraded three levels: suboptimal quality, inconsistency, and imprecision
2 Downgraded three levels: single study, suboptimal quality, and imprecision
3 Downgraded two levels: suboptimal quality of studies and imprecision