Summary of findings 5. Straight versus coiled catheters for preventing catheter‐related infections in chronic peritoneal dialysis patients.
| Straight versus coiled catheters for preventing catheter‐related infections in chronic peritoneal dialysis patients | |||||
| Patient or population: chronic peritoneal dialysis patients Intervention: straight Comparison: coiled | |||||
| Outcomes | Anticipated absolute effects* (95% CI) | Relative effect (95% CI) | No. of participants or patient‐months (studies) | Certainty of the evidence (GRADE) | |
| Risk with coiled | Risk with straight | ||||
| Peritonitis | 217 per 1,000 | 225 per 1,000 (178 to 284) | RR 1.04 (0.82 to 1.31) | 818 (9) | ⊕⊕⊕⊝ MODERATE 1 |
| Peritonitis rate (patient‐months) | 32 per 1,000 | 29 per 1,000 (22 to 39) | RR 0.91 (0.68 to 1.21) | 5882 (5) | ⊕⊕⊕⊝ MODERATE 1 |
| Exit‐site/tunnel infection | 281 per 1,000 | 314 per 1,000 (264 to 376) | RR 1.12 (0.94 to 1.34) | 826 (10) | ⊕⊕⊕⊝ MODERATE 1 |
| Exit‐site/tunnel infection rate (patient‐months) | 27 per 1,000 | 28 per 1,000 (21 to 39) | RR 1.05 (0.77 to 1.43) | 5286 (4) | ⊕⊕⊕⊝ MODERATE 1 |
| Catheter removal or replacement | 249 per 1,000 | 276 per 1,000 (181 to 413) | RR 1.11 (0.73 to 1.66) | 713 (9) | ⊕⊝⊝⊝ VERY LOW 1 2 3 |
| Technique failure | 131 per 1,000 | 108 per 1,000 (67 to 172) | RR 0.82 (0.51 to 1.31) | 442 (4) | ⊕⊕⊕⊝ MODERATE 1 |
| Death (all causes) | 124 per 1,000 | 117 per 1,000 (77 to 180) | RR 0.95 (0.62 to 1.46) | 703 (8) | ⊕⊕⊝⊝ LOW 1 3 |
| *The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio | |||||
| GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect | |||||
1 Downgraded one level: most studies are of suboptimal quality
2 Downgrade one level: inconsistency
3 Downgraded one level: publication bias