Timely PD 2010.

Methods	Study design: parallel RCT Study time frame/recruitment period: 1 March 2008 to 31 May 2013 Follow‐up period: day 180 post catheter insertion
Participants	Country: Australia Setting: multicentre (2 sites) ESKD patients over 18 years of age, who will be receiving CAPD or APD within 4 weeks of insertion of a PD catheter Number: treatment group 1 (39); treatment group (42); control group (41) Mean age ± SD (years): treatment group 1 (60.92 ± 15.2); treatment group 2 (57.55 ± 17.9); control group (54.41 ± 15.5) Sex (M/F): treatment group 1 (22/17); treatment group 2 (20/22); control group (26/15) Diabetes: treatment group 1 (15/39); treatment group 2 (14/42); control group (14/41) Exclusion criteria: a history of psychological illness or condition which resulted in inability to understand or comply with the requirements of the study or if there is an acute infectious episode in the last month before enrolment
Interventions	Treatment group 1 One‐week break‐in period Treatment group 2 Two‐week break‐in period Control group Four‐week break‐in period
Outcomes	Composite of exit‐site infection or tunnel tract or peritonitis Peritoneal fluid leak Technique failure
Notes	Funding source: "This study is partly funded by research grants from the Baxter Renal Division Clinical Evidence Council"
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomisation sequence was generated using STATA software (permuted block)
Allocation concealment (selection bias)	Low risk	Sealed envelopes
Blinding of participants and personnel (performance bias) All outcomes	High risk	Not blinded
Blinding of outcome assessment (detection bias) All outcomes	High risk	Not blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	No dropout
Selective reporting (reporting bias)	Low risk	Published protocol before study
Other bias	High risk	Protocol violation present