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. 2019 May 31;2019(5):CD004680. doi: 10.1002/14651858.CD004680.pub3

Trooskin 1990.

Methods
  • Study design: parallel RCT

  • Study time frame/recruitment period: not reported

  • Follow‐up period: not reported

Participants
  • Country: USA

  • Setting: multicentre (number of sites not reported)

  • Patients with CKD selected for PD

  • Number: treatment group (44); control group (42)

  • Mean age (years): treatment group (52); control group (49)

  • Sex (M/F): not reported

  • Diabetes: not reported

  • Exclusion criteria: known penicillin allergies

Interventions Treatment group
  • Surfactant‐treated catheter

  • Single and double‐cuff straight and spiral catheters were used. Catheters (BioGuard ABTM) pretreated with 5% tridodecylmethylammonium chloride (TDMAC) in ethanol


Control group
  • Surfactant‐untreated control catheter

Outcomes
  • Peritonitis

  • Exit‐site/tunnel infection

  • Death

  • Catheter related complication

  • Technique failure

Notes
  • Funding source: not reported

Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Double blinded
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Insufficient information to permit judgement
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Insufficient information to permit judgement
Selective reporting (reporting bias) Low risk Most of the outcomes of interest were reported
Other bias Unclear risk Insufficient information to permit judgement