Skip to main content
. 2019 Mar 29;11(6):1514–1524. doi: 10.1093/gbe/evz068

Table 2.

Maximum Likelihood Parameter Estimates for the Best-Fitting Models for INDELs in CDS Regions and Noncoding regions

Model and DFE Variant Type C θ γ Scale Shape ϵ α
(%)
CDS: equal mutation rate Insertions 1 4.92×106 –1.14 0.0799
Discrete C = 2 Insertions 2 0.000134 –801 0.000307 71
Ancestral repeat reference Deletions 1 8.32×106 –2.70 0.0368
Deletions 2 0.000206 –649 3.12×107 86
CDS: equal mutation rate Insertions 1 4.79×106 –0.264 0.0729
Discrete C = 2 Insertions 2 0.000156 –897 0.000526 63
Noncoding reference Deletions 1 7.79×106 –1.70 0.0366
Deletions 2 0.000205 –629 0.00587 79
Noncoding: free mutation rate Insertions 0.000170 –53.6 1,553 0.0345 0.0110
Continuous Deletions 0.000293 –75.5 715 0.106 0.0166

Note.—C defines the number of site class, θ the population scaled mutation rate, γ the population scaled selection coefficient, ϵ the polarization error, and α the proportion of INDEL substitutions driven by positive selection. Where γ values are presented for the continuous model these are mean γ estimates and the product of the scale and shape parameters.