Table 2.
Model and DFE | Variant Type | C | θ | γ | Scale | Shape | ϵ |
α
(%) |
---|---|---|---|---|---|---|---|---|
CDS: equal mutation rate | Insertions | 1 | –1.14 | — | — | 0.0799 | ||
Discrete C = 2 | Insertions | 2 | 0.000134 | –801 | — | — | 0.000307 | 71 |
Ancestral repeat reference | Deletions | 1 | –2.70 | — | — | 0.0368 | ||
Deletions | 2 | 0.000206 | –649 | — | — | 86 | ||
CDS: equal mutation rate | Insertions | 1 | –0.264 | — | — | 0.0729 | ||
Discrete C = 2 | Insertions | 2 | 0.000156 | –897 | — | — | 0.000526 | 63 |
Noncoding reference | Deletions | 1 | –1.70 | — | — | 0.0366 | ||
Deletions | 2 | 0.000205 | –629 | — | — | 0.00587 | 79 | |
Noncoding: free mutation rate | Insertions | — | 0.000170 | –53.6 | 1,553 | 0.0345 | 0.0110 | — |
Continuous | Deletions | — | 0.000293 | –75.5 | 715 | 0.106 | 0.0166 | — |
Note.—C defines the number of site class, θ the population scaled mutation rate, γ the population scaled selection coefficient, ϵ the polarization error, and α the proportion of INDEL substitutions driven by positive selection. Where γ values are presented for the continuous model these are mean γ estimates and the product of the scale and shape parameters.