Figure 4:

Selected one-way sensitivity analyses. Progression-free survival advantage, A, less than about 1 month and, D, overall survival advantage less than 0.5 months; B, probability of aphasia less than 9.36%, and, C, gross-total resection rate greater than 60% in the group that did not undergo intraoperative MRI made intraoperative MRI cost-ineffective at a willingness-to-pay threshold of $100 000. E, Duration of postoperative aphasia (maximum 84 months) can considerably reduce the incremental cost-effectiveness ratio (ICER; as low as $42 131 per quality-adjusted life year [QALY]), though intraoperative MRI is cost-effective regardless of the number of months of postoperative aphasia. F, Intraoperative MRI ceases to be cost-effective at a cost greater than $3500 per operation, which was about 1.5 times our upper-limit cost.