Skip to main content
. 2019 May 22;13:497. doi: 10.3389/fnins.2019.00497

FIGURE 10.

FIGURE 10

Phototoxicity marks in the trigeminal pathway. (A–C) Results of RT-qPCR analysis on the TGs: mRNA expression of cFOS (A), Iba1 (B), and ATF3 (C). Statistical significance: cFOS: blue no recovery vs. recovery – q = 0.0129, p = 0.0061; yellow no recovery vs. recovery – q = 0.0339, p = 0.0323; ATF3: blue no recovery vs. recovery – q = 0.0076, p = 0.0072; recovery blue vs. yellow – q = 0.0243, p = 0.0231. (D–F) Results of RT-qPCR analysis on the brainstems: mRNA expression of cFOS (D; blue no recovery vs. recovery – q < 0.0001, p < 0.0001; yellow no recovery vs. recovery – q < 0.0001, p < 0.0001), Iba1 (E) and ATF3 (F). Blue and yellow bars correspond to blue and yellow exposures, respectively; clear and hatched bars correspond to the time points of mice dissection, either directly after illumination (no recovery) or in 3 days of recovery (recovery), respectively. All the data are presented as mean ± SEM. Differences were considered significant when p < 0.05 (∗/∧), p < 0.01 (∗∗/∧∧), p < 0.001 (∗∗∗/∧∧∧) or p < 0.0001 (∗∗∗∗/∧∧∧∧). Stars correspond to comparisons between blue-illuminated and yellow-illuminated mice, treated with the same drug. Carets correspond to comparison of mice assessed directly after illumination to the ones after 3 days of recovery, within the same spectra. Red color means increase and blue color decrease in values.