Table 2.

Name, manufacturer, method, and time of application (relative to the beginning of light exposure) and bibliographic reference (if applicable).

Drug	References	Time before exposure	Method of use	Literature
PBS	Life Technologies, Carlsbad, CA, United States	Directly before	Instillation or ivt injection	NA
Atropine sulfate 1%	Europhta, Monaco	5 min	Instillation	Okamoto et al., 2011; Matynia et al., 2012
Pilocarpine nitrate 1%	Europhta, Monaco	15 min	Instillation	NA
Visual receptors (VR) blocker	See below	5 min	ivt injection	Bush and Sieving, 1994; Gregory Gauvain, personal communication
opn4 antagonist 30 mg/kg	Merck, St Quentin en Yvelines, France	15 min	ip injection	Xue et al., 2012; Jones et al., 2013
DMSO HYBRI-MAX	Sigma-Aldrich, St. Louis, MO, United States	15 min	ip injection	NA
Oxybuprocaine hydrochloride 1.6 mg/0.4 mL	Thea, Clermont-Ferrand, France	Directly before	Instillation	NA
Lidocaine hydrochloride 2%	Aguettant, Lyon, France	5 min	ivt injection	Okamoto et al., 2011
DL-norepinephrine hydrochloride 10 mM (Supplementry Figure S7)	Sigma-Aldrich, St. Louis, MO, United States	5 min	ivt injection	Okamoto et al., 2011

NA, not applicable.