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. 2019 May 24;10:1022. doi: 10.3389/fmicb.2019.01022

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Copyright © 2019 Beyß, Azzouzi, Weitzel, Wiechert and Nöh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Isotopic substrate labeling profiles. Showcased are a simple repetitive switch between fully (red solid line) and naturally labeled glucose (blue dashed line) specified via a Boolean condition for each time interval (A), a sinus with wavelength 2π (B), and an exponential enrichment-decay curve (C). Shown are fractional labeling enrichments (FLE). The species of each input pool must sum up to 1.0 to define a valid profile. Contributions attributed to impurities are not displayed in the charts.