Table 1.
Clinical characteristics of patients with and without RI
| Characteristics | Total population | RI | Control group | P |
|---|---|---|---|---|
| n = 153 | n = 45 | n = 108 | ||
| Clinical data | ||||
| Age, years, mean (SD) | 54.6 (18.2) | 56.2 (19.7) | 54 (17.4) | 0.57 |
| Male gender | 56 (37) | 27 (60) | 29 (27) | <0.0001 |
| Years since diagnosis, mean (SD) | 1.46 (3.4) | 2.0 (4.8) | 1.2 (2.5) | 0.22 |
| Diabetes | 17 (11) | 13 (29) | 4 (4) | <0.0001 |
| Purpura | 41 (27) | 17 (38) | 24 (22) | 0.048 |
| Acrosyndrome | 18 (12) | 3 (7) | 15 (14) | 0.21 |
| Arthralgia | 30 (20) | 5 (11) | 25 (23) | 0.09 |
| Neurological involvement | 21 (14) | 7 (16) | 14 (13) | 0.67 |
| Hypertension | 28 (18) | 19 (42) | 9 (9) | <0.0001 |
| Aetiologies | ||||
| Secondary cryoglobulinaemia | 114 (75) | 29 (64) | 85 (79) | 0.07 |
| Lymphoproliferative disorders | 20 (13) | 10 (22) | 10 (9) | 0.03 |
| Autoimmune disease | 74 (48) | 12 (27) | 62 (58) | 0.001 |
| Infectious disease | 28 (18) | 10 (22) | 18 (17) | 0.42 |
| Hepatitis C virus | 21 (14) | 7 (16) | 14 (13) | 0.67 |
Data are presented as n (%) unless otherwise indicated.