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. 2019 Mar-Apr;94(2 Suppl 1):20–32. doi: 10.1590/abd1806-4841.2019940206

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This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.

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Treatment algorithm for pemphigus vulgaris

PV: pemphigus vulgaris; AZA: azathioprine; MMF: mycophenolate mofetil; IVIG: intravenous immunoglobulin

PV only in mucous membrane:

Mild: only in oral mucosa/ Moderate: extensive lesions in oral mucosa/ Severe: lesions in oral mucosa and others (for example, esophagus, larynx)

PV mucocutaneous:

Mild: < 1% de BSA / Moderate: 1 - 10% of BSA / Severe: > 10% of BSA:

BSA: body surface area (1% means the sum of injured areas corresponding to the palmar surface of the hand with the five digits)

* This severity rating is not definitive and aims to provide initial guidance. Each case should be evaluated individually, including considering the speed of onset and progression of the lesions, comorbidities, contraindications to the use of corticosteroids and response to the treatment applied.

** Prednisone can be replaced by oral prednisolone