Fig. 3. SEM images of captured exosomes on ExoProfile chip. (a) Large amount of exosomes captured on anti-CD81 antibodies immobilized 3D beads assembled nanostructures, and (b) minimized non-specific adsorption of exosomes on BSA coated control chip. (c) Less exosomes captured on the flat glass surface adjacent to the nanostructures. (d) Silica beads beneath the surface layer of nanostructures also captured exosomes.