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Fig. 3. (a) The blood circulation of and (b) biodistribution of Re NCs in major organs after intravenous injection (0.1 mL, 2 mg mL–1) in ICR mice (n = 5). (c) Schematic of the renal clearance process of Re NCs; (d) renal clearance efficiencies of Au NPs, Re NCs and NH4ReO4 24 h after injection (2 mg mL–1, 0.2 mL); inset is the TEM image of Au NPs (mean ± s.d., ***p < 0.001).