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CLEAR 1 study. Serum urate (UA) levels at each study visit throughout 12 months. The mean change from baseline (BL) for the group receiving lesinurad 200 mg plus allopurinol was significant as compared with allopurinol alone (p<0.0001) for each comparison at each timepoint tested. Adapted from Saag et al.21
UA, uric acid.
