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. 2019 May 31;14(5):e0216793. doi: 10.1371/journal.pone.0216793

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© 2019 Borys et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — A. Pathway enrichment comparison performed in ClueGO plugin for Cytoscape software on 481 differentially expressed genes from T3 vs. T1 comparison. Green–downregulated, pink–upregulated genes; the size of the node is inversely proportional to the term p-value. B. Pathway enrichment performed in ClueGO plugin for Cytoscape on gene set with LogFoldChange > |1.5| and adjusted p value < 0.05. C. Heatmap of differentially expressed genes in T3 vs T1 comparison. Based on the expression pattern the samples were divided into three clusters. Color bar indicates what cluster the sample was assigned to: red–A1 (pure T1), green–A3 (pure T3), blue–A2 (mixed).