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. 2019 May 31;14(5):e0217339. doi: 10.1371/journal.pone.0217339

Fig 4. Influence of ws-Lynx1 on the growth of A549 cells.

Fig 4

(A). Effects of ws-Lynx1 on the growth of A549 cells during 24-, 48- and 72-hour incubation. The data are expressed as % of the control (untreated cells). Each point is a mean ± S.E.M. of 4–10 independent experiments. (B). The influence of ws-Lynx1, the inhibitors of different receptors, and nicotine on the viability of A549 cells. (C). Effects of ws-Lynx1 and inhibitors of intracellular signaling cascades on the A549 cells viability. Cells in (B,C) were incubated with ws-Lynx1 and other compounds during 72 hours as described in the Materials and Methods section. The data are mean ± SEM, n = 4–8; ## (p<0.01), ### (p<0.001), and #### (p<0.0001) indicate the significant difference from the control (100%) by a two-tailed one sample t-test; && (p<0.01) indicates the significant difference between the “Nicotine” and “ws-Lynx1 + Nicotine” groups by a two-tailed t-test; * (p<0.05), ** (p<0.01), *** (p<0.001), and **** (p<0.0001) indicate the significant difference between the “ws-Lynx1” and “ws-Lynx1 + agonist/inhibitor” groups by One-way ANOVA followed by a Dunnet’s post hoc test. The control level (100% of viable cells) corresponds to the untreated cells.