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. 2019 May 31;14(5):e0217617. doi: 10.1371/journal.pone.0217617

Fig 3. Number and risk of bias of studies with acceptable research designsa over time.

Fig 3

a Study designs eligible for the review included pre- versus post-intervention studies with a randomized or non-randomized comparison group, post-intervention only studies with a randomized comparison group, and interrupted time series with at least three data points before and after the intervention.