Table 3. Association analysis between exonic APOB variants and oxLDL levels.

	Rare variants (MAF<0.01)					Rare and low-frequency variants (MAF<0.05)
Test	WST	SKAT	SKAT with covariates	SKAT-O	SKAT-O with covariates	WST	SKAT	SKAT with covariates	SKAT-O	SKAT-O with covariates
Deleterious/damaging*	0.244	0.464	0.358	0.645	0.443	0.623	0.037	0.004	0.043	0.006
Nonsynonymous	0.829	0.164	0.048	0.253	0.089	0.813	0.164	0.034	0.278	0.065
Synonymous & nonsynonymous	0.789	0.087	0.034	0.126	0.064	0.173	0.017	0.003	0.034	0.006

*By SIFT and PolyPhen-2 algorithms.