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. 2019 May 31;14(5):e0217640. doi: 10.1371/journal.pone.0217640

Fig 6. In vitro cancer drug screening.

Fig 6

Effectiveness of chemotherapeutic drug treatment on A549 2D monolayer grown on TCPS and porous PLGA particles was quantified using LDH assays. It was observed that cancer drugs reduced only ~20–30% of A549 growth on the particles compared to its 2D counterparts when treated with the same concentrations of drugs. The percentage of A549 cell death was calculated with respect to untreated cells (N/T) lysed with triton. Data was statistically significant (n = 3, *p<0.05) when compared between two models (2D vs. particles) for each treatment groups.