Figure 3: TTC staining of brains in safety study groups.
Infarct is identified by pale areas denoted by the black arrows. These TTC brain cross-sections are representative results of animals in the high-dose (A), medium-dose (B), low-dose (C), and control (D – no MBs) groups. Significant gas embolism resulted in group A, which led to lasting infarct and brain tissue loss.