Table 3.
Gene/Protein | Description | Fold changea (1.25% vs 0.5%) |
---|---|---|
HP0003 | 3-deoxy-d-manno-octulosonic acid 8-phosphate synthetase (KdsA) | 0.61 |
HP0089 | Pfs; Mtn; MqnB | 0.50 |
HP0204 | hypothetical protein | 0.54 |
HP0618 | adenylate kinase (Adk) | 0.46 |
HP0630 | modulator of drug activity (Mda66) | 0.57 |
HP0865 | deoxyuridine 5’-triphosphate nucleotidohydrolase (Dut) | 0.60 |
HP0871 | CDP-diglyceride hydrolase (Cdh) | 2.77 |
HP0887 | vacuolating cytotoxin (VacA) | 1.81 |
HP1098 | hypothetical secreted protein (HcpC) | 0.35 |
HP1099 | 2-keto-3-deoxy-6-phosphogluconate aldolase (Eda) | 0.58 |
HP1117 | hypothetical secreted protein (HcpX) | 0.54 |
HP1118 | gamma-glutamyltranspeptidase (Ggt) | 0.49 |
HP1186 | carbonic anhydrase | 1.85 |
HP1299 | methionine amino peptidase (Map) | 0.54 |
HP1458 | thioredoxin-2 (Trx2) | 0.43 |
HP1469 | outer membrane protein (Omp31, HorJ) | 0.59 |
H. pylori was grown in Brucella broth containing either 0.5% or 1.25% NaCl. RNA-seq was performed as described in the methods. The fold change in transcript levels in response to high salt conditions was then calculated as a ratio (number of RNA-seq reads from cultures containing 1.25% NaCl compared to reads from cultures containing 0.5% NaCl).