Figure 11. Efficacy of FEO on drug metabolizing enzymes of acetaminophen induced hepatic injured mice: Values are expressed as mean ± SD (n = 8) animals.

^*p < 0.05, ^**p < 0.01 represent significant changes against control. Group I: Untreated control and fed orally with distilled water daily for seven days. Group II: Mice treated with FEO 250 mg/kg body weight. Group III: Mice treated with FEO 500 mg/kg body. Group IV: Mice treated with 0.75% BHA along with diet (positive control). (A) CytP450 and Cytb5, (B) GST. BHA – butylated hydroxyanisole; Cyt P450 – Cytochrome P450; Cyt b5 – Cytochrome b5; GST – Glutathione S-transferase.