Table 1:
HC (N = 64) | PSD (N = 150) | SP (N = 93) | SA (N = 15) | BP-I (N = 42) | |||
---|---|---|---|---|---|---|---|
Mean (SD) | Mean (SD) | p value | Mean (SD) | Mean (SD) | Mean (SD) | p value | |
Demographics | |||||||
Sex (Females/Males) | 24/40 | 56/94 | p = 0.982 | 32/61 | 5/10 | 19/23 | p = 0.457 |
Age (years) | 32.67 (7.96) | 32.31 (9.07) | p = 0.784 | 31.51 (8.54) | 32.53 (9.65) | 34.02 (9.96) | p = 0.329 |
Education (years) | 14.98 (2.20) | 13.34 (2.39) | p < 0.001 | 13.01 (2.48) | 12.93 (1.94) | 14.21 (2.14) | p = 0.019 |
FTND | 0.50 (1.41) | 1.51 (2.43) | p < 0.001 | 1.72 (2.53) | 1.50 (2.35) | 1.05 (2.22) | p = 0.340 |
Cognition | |||||||
WTAR | 56.40 (6.86) | 51.24 (10.57) | p < 0.001 | 49.11 (11.25) | 53.69 (8.98) | 55.06 (8.20) | p = 0.006 |
Attention | 46.19 (9.68) | 36.53 (12.90) | p < 0.001 | 35.60 (12.60) | 35.73 (9.51) | 38.86 (14.49) | p = 0.404* |
Processing speed | 50.05 (10.07) | 39.25 (11.49) | p < 0.001 | 38.22 (11.93) | 38.07 (10.57) | 41.95 (10.58) | p = 0.211* |
Working memory | 47.28 (9.43) | 39.63 (11.58) | p < 0.001 | 38.06 (11.96) | 39.00 (12.02) | 43.31 (9.88) | p = 0.040* |
Declarative memory | 48.35 (8.59) | 37.57 (10.41) | p < 0.001 | 35.43 (10.32) | 40.02 (10.18) | 41.44 (9.56) | p = 0.002* |
General Cognitive Ability | 0.68 (0.72) | −0.29 (0.96) | p < 0.001 | −0.43 (0.98) | −0.22 (0.91) | 0.00 (0.91) | p = 0.041* |
Functioning | |||||||
UPSA-B total | 77.51 (11.84) | 68.73 (15.78) | p < 0.001 | 65.25 (15.97) | 70.77 (14.30) | 75.70 (13.56) | p = 0.002* |
S-QoL 18 | 66.49 (9.59) | 56.69 (14.41) | p < 0.001 | 57.13 (13.97) | 57.55 (14.05) | 55.41 (15.70) | p = 0.631* |
SLOF-I total | 87.43 (17.60) N=110 |
85.14 (17.50) N=68 |
73.00 (19.36) N=9 | 96.09 (13.15) N=33 |
p = 0.045* |
Notes: HC = Healthy controls; PSD = Psychotic Spectrum Disorders; SP = Patients with schizophrenia; SA = Patients with schizoaffective disorder; BP-I = Patients with bipolar disorder, Type I; FTND = Fagerstrom Test for Nicotine Dependence; WTAR = Wechsler Test of Adult Reading; UPSA-B = UCSD Performance Based Skills Assessment Brief Version; S-QoL 18 = Quality of Life Questionnaire in Schizophrenia 18; SLOF-I = Specific Levels of Functioning Informant Scale;