Table 4:
Summary of results from regression analyses using measures of function as dependent variables.
| Function | DSM and Sx Burden (Model 1) | DSM (Model 2) | Sx Burden (Model 3) | Sx Burden Clust (Model 4) |
|---|---|---|---|---|
| UPSA-B | ||||
| ΔR2 (p value) | 0.222 (< 0.001) | 0.056 (0.002) | 0.221 (<0.001) | 0.133 (<0.001) |
| IV: Beta (p value) | DSM = 0.065 (0.634) | DSM = 0.244 (0.002) | DSM = NA | Sx Clust = −0.376 (<0.001) |
| Positive = −0.048 (0.516) | Positive = NA | Positive = −0.051 (0.492) | ||
| Negative = −0.439 (< 0.001) | Negative = NA | Negative = −0.441 (<0.001) | ||
| SBS = −0.050 (0.711) | SBS = NA | SBS = −0.104 (0.172) | ||
| S-QoL 18 | ||||
| ΔR2 (p value) | 0.010 (0.849) | 0.002 (0.631) | 0.010 (0.711) | 0.008 (0.292) |
| IV: Beta (p value) | DSM = 0.000 (0.998) | DSM = −0.041 (0.631) | DSM = NA | Sx Clust = −0.090 (0.292) |
| Positive = −0.087 (0.330) | Positive = NA | Positive = −0.087 (0.326) | ||
| Negative = −0.002 (0.983) | Negative = NA | Negative = −0.002 (0.983) | ||
| SBS = 0.073 (0.657) | SBS = NA | SBS = 0.072 (0.426) | ||
| SLOF-I | ||||
| ΔR2 (p value) | 0.096 (0.018) | 0.033 (0.045) | 0.095 (0.008) | 0.063 (0.005) |
| IV: Beta (p value) | DSM = −0.049 (0.777) | DSM = 0.191 (0.045) | DSM = NA | Sx Clust = −0.257 (0.005) |
| Positive = −0.095 (0.320) | Positive = NA | Positive = −0.092 (0.331) | ||
| Negative = −0.214 (0.034) | Negative = NA | Negative = −0.213 (0.034) | ||
| SBS = −0.170 (0.330) | SBS = NA | SBS = −0.130 (0.195) | ||
| B-SNIP SFS | ||||
| ΔR2 (p value) | 0.185 (< 0.001) | 0.048 (<0.001) | 0.182 (<0.001) | 0.130 (<0.001) |
| IV: Beta (p value) | DSM = 0.069 (0.143) | DSM = 0.229 (<0.001) | DSM = NA | Sx Clust = 0.363 (<0.001) |
| Positive = −0.141 (0.003) | Positive = NA | Positive = −0.151 (0.001) | ||
| Negative = −0.323 (< 0.001) | Negative = NA | Negative = −0.342 (<0.001) | ||
Notes: DSM = Diagnostic and Statistical Manual of Mental Disorders Diagnoses (i.e. schizophrenia, schizoaffective disorder, or bipolar disorder, Type I); Sx Burden = symptom burden based on the Positive and Negative Syndrome Scale (PANSS) and the Schizo-Bipolar Scale (SBS) scores; Sx Burden Clust = three clusters of PANSS positive and negative symptom scores; UPSA-B = UCSD Performance Based Skills Assessment Brief Version; S-QoL 18 = Quality of Life Questionnaire in Schizophrenia 18; SLOF-I = Specific Levels of Functioning Informant Scale; IV = independent variables; Positive = PANSS positive symptom score; Negative = PANSS negative symptom score; SBS = Schizo-Bipolar Scale; B-SNIP = Bipolar and Schizophrenia Network on Intermediate Phenotypes; SFS = Social Functioning Scale. Beta values are standardized.