Table 1.
Baseline Characteristics and Clinical and Imaging Features
| Variable | All (n=113) | Heparin (n=59) | Non-heparin (n=54) | P value |
|---|---|---|---|---|
| Age | 70 (53, 79) | 70 (51.5, 78.5) | 71 (54.5, 81.7) | 0.42 |
| Gender Male | 70 (61.9%) | 38 (64.4%) | 32 (59.3%) | 0.71 |
| Admission Glucose (mg/dL) | 118 (105, 137) | 117 (106, 128) | 122 (104, 147) | 0.36 |
| Admission SBP (mmHg) | 153 (25.2) | 154 (24) | 153 (27) | 0.90 |
| Admission NIHSS | 7.5 (4, 14) | 6 (3, 11.5) | 11 (6, 15.5) | 0.04 |
| CCS Subtypes | 0.29 | |||
| - Large artery | 25 (22%) | 16 (27%) | 9 (17%) | 0.25 |
| - Cardioembolic | 53 (47%) | 23 (39%) | 30 (55%) | 0.09 |
| - Other | 16 (14%) | 10 (17%) | 6 (11%) | 0.42 |
| - Cryptogenic | 19 (17%) | 10 (17%) | 9 (17%) | 1.0 |
| Arterial Territory Involved | 0.42 | |||
| - ICA | 7 (6%) | 3 (5%) | 4 (7%) | 0.70 |
| - ACA | 4 (3%) | 2 (3%) | 2 (4%) | 1.0 |
| - MCA | 92 (81%) | 49 (83%) | 43 (80%) | 0.8 |
| - PCA | 5 (5%) | 1 (2%) | 4 (7%) | 0.19 |
| - VB | 5 (5%) | 4 (7%) | 1 (2%) | 0.36 |
| Large Vessel Occlusion | 0.31 | |||
| - Complete | 50 (44%) | 25 (42%) | 25 (46%) | 0.45 |
| - Partial | 14 (12%) | 10 (17%) | 4 (7%) | 0.15 |
| Time to first MRI (h) | 6.0 (2.7) | 6.2 (2.5) | 5.7 (2.8) | 0.36 |
| Admission DWI vol. (mL) | 17.2 (5, 50) | 12.9 (4, 30) | 26.8 (8, 60) | 0.03 |
| Admission Mismatch vol. (mL) | 93.6 (46, 174) | 88.3 (40, 183) | 95.1 (51, 137) | 0.99 |
| Percent Mismatch (%) | 548 (169, 2053) | 770 (228, 2074) | 293 (120, 1675) | 0.069 |
| Time to follow-up exam (days) | 9.7 (5.9, 37.6) | 10.1 (6.1, 34) | 9.4 (5.5, 42.7) | 0.79 |
| Final infarct volume (mL) | 28.7 (9.6, 90.9) | 17.4 (7.6, 51.8) | 56.6 (15.1, 107) | 0.004 |
| Absolute Lesion Growth (mL) | 8.48 (0.1, 41.5) | 4.7 (−1.1, 15.2) | 20.5 (2.4, 54.2) | 0.009 |
| Percentage Mismatch Lost (%) | 7.4 (0.1, 31.2) | 3.5 (−0.9, 17.0) | 19.2 (2.6, 56.0) | 0.002 |
| Discharge mRS 0–2 | 37 (33%) | 25 (43%) | 12 (22%) | 0.03 |
| 90-day mRS 0–2 | 53 (47%) | 30 (73%) | 23 (55%) | 0.13 |
Abbreviations: SBP: Systolic blood pressure; NIHSS: National Institutes of Health Stroke Scale; CCS: Causative Classification System; ICA: Internal carotid artery; ACA: anterior cerebral artery; MCA: top cerebral artery; PCA: posterior cerebral artery; VB, vertebro-basilar arteries; Vol, volume.