Table 2.
Univariable Predictors of Infarct Growth
| Variable | PML (Median, IQR or Correlation Coefficient) | P value | Absolute Lesion Growth (mL, Median, IQR or Correlation Coefficient) | P value |
|---|---|---|---|---|
| Age | 0.12 | 0.19 | 0.14 | 0.15 |
| Gender: | 0.28 | 0.19 | ||
| - Male | 10.2% (1.6%, 37.0%) | 10.7 (1.0, 44.9) | ||
| - Female | 5.1% (−0.5%, 20.7%) | 6.5 (−0.4, 20.4) | ||
| Admission Glucose | 0.29 | 0.002 | 0.28 | 0.003 |
| Admission SBP | 0.008 | 0.94 | 0.05 | 0.59 |
| NIHSS score | 0.21 | 0.06 | 0.27 | 0.01 |
| CCS Subtypes | 0.20 | 0.01 | ||
| - Large-artery (n=25) | 9.7% (2.3%, 27.4%) | 14.3 (4.1, 56.9) | ||
| - Cardioembolic (n=53) | 7.8% (−0.9%, 30.7%) | 6.5 (−0.8, 22.9) | ||
| - Other (n=16) | 21.6% (4.3%, 50.4%) | 27.7 (9.2, 63.6) | ||
| - Cryptogenic (n=19) | 1.6% (−9.3%, 27.7%) | 0.5 (−5.9, 22.9) | ||
| Stroke territory | 0.20 | 0.36 | ||
| - ICA | 7.9% (4.4%, 57.8%) | 13.6 (8.3, 49.8) | ||
| - ACA | 1.2% (−2.1%, 25.3%) | 0.5 (−0.5, 17.2) | ||
| - MCA | 7.6% (0.4%, 29.6%) | 8.5 (0.2, 43.2) | ||
| - PCA | 72.1% (30.7%,136%) | 16.0 (8.0, 23.2) | ||
| - VB | 0.0% (−7.5%, 3.5%) | 0.0 (−6.6, 3.6) | ||
| Proximal-artery occlusion | 0.07 | <0.001 | ||
| - Yes | 9.5% (2.5%, 29.9%) | 14.1 (3.9, 53.4) | ||
| - No | 2.7% (−8.8%, 31.4%) | 2.1 (−4.1, 18.2) | ||
| Time to MRI | −0.11 | 0.24 | −0.09 | 0.36 |
| Admission DWI volume | 0.27 | 0.003 | 0.29 | 0.002 |
| Heparin | 0.002 | 0.009 | ||
| - Yes | 3.5% (−1.0%, 17.1%) | 4.7 (−1.2–15.3) | ||
| - No | 19.2% (2.6%, 56.1%) | 20.5 (2.4–54.2) | ||
Abbreviations: SBP: Systolic blood pressure; NIHSS: National Institutes of Health Stroke Scale; CCS: Causative Classification System; ICA: Internal carotid artery; ACA: anterior cerebral artery; MCA: middle cerebral artery; PCA: posterior cerebral artery; VB, vertebrobasilar arteries; PTT, partial thromboplastin time.