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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Schizophr Res. 2019 Apr 13;208:49–54. doi: 10.1016/j.schres.2019.04.010

Table 3:

Summary of correlations between cognitive tests and fractional anisotropy (FA) in FEP, S-FEP, and healthy controls (HC). Correlations were accessed using the cognitive test scores, (“cog. score”), as well as the scores adjusted for age, gender, and race (“adj. cog. score”). “R2adj” and “P” are the r squared adjusted and p-value for the linear model fitting the correlation between regional FA and cognition; “P-mv” is the p-value for the partial correlation between regional FA and cognition, including age, race, gender, and antipsychotic dosage as covariates; “P-gr.sl.” is the p-value for the difference between the group slopes (S-FEP vs. controls, or FEP vs. controls).

Processing Speed Attention / Working Memory Executive Functioning
Cerebral peduncle Inferior temporal Angular left Supramarginal Left Superior occipital Inferior occipital Sagittal striatum External capsule / Insula Uncinate right Cingulum left Rectus left Retrolenticular int. capsule right Sagittal striatum right
S-FEP cog. score R2adj 0.164 0.121 0.155 0.153 0.174 0.135 0.14 0.124 0.093 0.146 0.075 0.118 0.159
P 0.001 0.004 0.001 0.001 0.001 0.003 0.002 0.004 0.012 0.002 0.021 0.005 0.001
P-mv 0.001 0.01 0.0002 0.002 0.001 0.004 0.0004 0.0009 0.021 0.0003 0.002 0.0009 0.001
P-gr.sl. 0.003 0.005 0.012 0.016 0.003 0.004 0.005 0.006 0.43 0.006 0.089 0.18 0.051
adj. cog. score R2adj 0.216 0.146 0.185 0.121 0.148 0.092 0.134 0.147 0.103 0.122 0.095 0.101 0.132
P 0.0001 0.002 0.0005 0.004 0.002 0.012 0.003 0.002 0.008 0.004 0.011 0.009 0.003
P-mv 0.0007 0.008 0.0001 0.005 0.003 0.005 0.0004 0.0005 0.012 0.0004 0.004 0.0005 0.0008
P-gr.sl. 0.003 0.002 0.002 0.004 0.029 0.002 0.025 0.005 0.09 0.018 0.042 0.06 0.064
FEP cog. score R2adj 0.129 0.085 0.088 0.111 0.133 0.066 0.049 0.117 0.094 0.107 0.039 0.07 0.049
P 0.0002 0.004 0.003 0.001 0.0007 0.01 0.023 0.001 0.002 0.001 0.038 0.008 0.023
P-mv 0.0002 0.004 0.001 0.0009 0.0006 0.006 0.004 0.0007 0.0146 0.0005 0.02 0.003 0.048
P-gr.sl. 0.003 0.015 0.04 0.049 0.011 0.026 0.04 0.008 0.43 0.01 0.222 0.286 0.334
adj. cog. score R2adj 0.145 0.085 0.091 0.072 0.11 0.039 0.044 0.122 0.073 0.109 0.06 0.068 0.032
P 0.0001 0.004 0.003 0.007 0.001 0.039 0.029 0.001 0.007 0.001 0.013 0.009 0.038
P-mv 0.0002 0.003 0.001 0.003 0.001 0.007 0.003 0.005 0.009 0.0005 0.022 0.003 0.048
P-gr.sl. 0.008 0.009 0.01 0.022 0.016 0.009 0.034 0.0004 0.137 0.027 0.181 0.127 0.377
HC cog. score R2adj −0.011 −0.01 −0.004 −0.011 −0.01 −0.005 −0.01 −0.009 0.021 −0.005 −0.006 0.028 0.001
P 0.93 0.764 0.446 0.955 0.74 0.458 0.835 0.686 0.089 0.815 0.486 0.058 0.31
P-mv 0.72 0.651 0.465 0.557 0.588 0.539 0.848 0.204 0.512 0.822 0.408 0.125 0.474
adj. cog. score R2adj −0.01 −0.011 −0.005 −0.004 −0.01 0.01 −0.009 0.017 −0.007 −0.001 −0.001 0.005 −0.003
P 0.754 0.862 0.477 0.436 0.818 0.163 0.719 0.108 0.54 0.629 0.344 0.233 0.395
P-mv 0.746 0.607 0.556 0.43 0.523 0.769 0.95 0.154 0.582 0.838 0.447 0.163 0.514