. Author manuscript; available in PMC: 2020 Jul 1.

Published in final edited form as: Ann Biomed Eng. 2019 Apr 8;47(7):1539–1551. doi: 10.1007/s10439-019-02262-9

Table 2:

Summary of model variations

	Model Name	k_p,T	k_p,V	Calibrated Parameters
Reaction Diffusion	N_T,m0	global	NA	3

Coupled via cell death	N_T,m1 and N_V,m1	global	global	10
	N_T,m2 and N_V,m2	local	global	9 + m
	N_T,m3 and N_V,m3	global	local	9 + m
	N_T,m4 and N_V,m4	local	local	8 + 2 × m

Coupled via carrying capacity	N_T,m5 and N_V,m5	global	global	9
	N_T,m6 and N_V,m6	local	global	8 + m
	N_T,m7 and N_V,m7	global	local	8 + m
	N_T,m8 and N_V,m8	local	local	7 + 2 × m

m is equal to the number of calibrated local parameters within the tumor. m ranged from 202 to 461, depending on the animal.