Table 1. Inclusion of cases for ultrasensitive sequencing.
Study | N patients (only blood) | N patients (only brain) | N patients (blood + brain) | Total N patients | Mean age at onset (range) | Mean age at death (range) |
---|---|---|---|---|---|---|
Rouen CNRMAJ, France | 347 | 2* | 2† | 351 | 54.42 (44–65) | NA |
MRC Brain Bank, UK | 0 | 80 | 0 | 80 | 69.9 (53–82)‡ | 85 (71–99) |
Netherlands Brain Bank | 0 | 8 | 6 | 14 | 56.4 (48–63)§ | 66.9 (57–75) |
Total | Total blood samples: 355 form 355 patients | 445 | ||||
Total brain samples: 100 from 98 patients |
Abbreviation: MRC, Medical Research Council.
One sample from cerebellum and one sample from frontal cortex for one patient, one sample from an unspecified region for the second patient.
One sample from cerebellum and one sample from frontal cortex in one patient, one sample from frontal cortex for the second patient.
Among the 29/80 patients with available information.
Among the 12/14 patients with available information.