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. Author manuscript; available in PMC: 2019 May 31.
Published in final edited form as: Alzheimers Dement. 2018 Aug 13;14(12):1632–1639. doi: 10.1016/j.jalz.2018.06.3056

Table 1. Inclusion of cases for ultrasensitive sequencing.

Study N patients (only blood) N patients (only brain) N patients (blood + brain) Total N patients Mean age at onset (range) Mean age at death (range)
Rouen CNRMAJ, France 347 2* 2 351 54.42 (44–65) NA
MRC Brain Bank, UK     0 80   0   80   69.9 (53–82)    85 (71–99)
Netherlands Brain Bank     0   8   6   14   56.4 (48–63)§ 66.9 (57–75)
Total Total blood samples: 355 form 355 patients 445
Total brain samples: 100 from 98 patients

Abbreviation: MRC, Medical Research Council.

*

One sample from cerebellum and one sample from frontal cortex for one patient, one sample from an unspecified region for the second patient.

One sample from cerebellum and one sample from frontal cortex in one patient, one sample from frontal cortex for the second patient.

Among the 29/80 patients with available information.

§

Among the 12/14 patients with available information.