Table 2. Association of SBP variability with unfavorable shift of the mRS at 90 days.
Univariate analysis | Multivariate Model | |||
---|---|---|---|---|
OR(95%CI) | P value | OR(95%CI) | P value | |
Mean | 1.26(1.21-1.31) | <0.0001 | 1.21(1.16-1.25) | <0.0001 |
MIN | 1.18(1.14-1.23) | <0.0001 | 1.15(1.11-1.20) | <0.0001 |
MAX | 1.28(1.23-1.33) | <0.0001 | 1.21(1.16-1.26) | <0.0001 |
SD | 1.17(1.12-1.23) | <0.0001 | 1.10(1.05-1.15) | <0.0001 |
CV | 1.11(1.06-1.15) | <0.0001 | 1.06(1.02-1.10) | 0.0065 |
ARV | 1.17(1.11-1.22) | <0.0001 | 1.12(1.06-1.17) | <0.0001 |
RSD | 1.13(1.08-1.18) | <0.0001 | 1.08(1.04-1.13) | 0.0002 |
VIM | 1.08(1.04-1.13) | <0.0001 | 1.04(1.00-1.08) | 0.0533 |
CV: coefficient of variation; ARV: average absolute difference between successive BP measurements; RSD: residual SD; VIM: variation independent of mean.
Data are presented as odds ratio [OR] (95% confidence intervals [95%CI]) for per 1 unit increment of systolic blood pressure [SBP] variability (i.e. for SD, the unit is 1 SD of SD; for CV, the unit is 1 SD of CV; for ARV, the unit is 1 SD of ARV; for RSD, the unit is 1 SD of RSD; and for VIM, the unit is 1 SD of VIM).
Multivariable Model: Adjusted for country, prestroke mRS score, sex, baseline NIHSS score, and history of heart disease, stroke, diabetes mellitus, or hypertension, prior antiplatelet therapy