Figure 4. Cy3-induced bending and twisting of DNA tile tubes.
a) A Cy3-modification on a DNA tile tube can act similar to a base pair insertion and lead to a helical shape of the structure. b) 6-helix tile tubes (6HTs) with three different arrangements of Cy3 dyes showed different bending and twisting as observed by fluorescence microscopy. Note that opposing Cy3 modifications reduced the total amount of bending whereas the induced twisting added up, which resulted in a helical shape with increased diameter and pitch. Scale bar: 2 μm
