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. 2019 May 31;9:156. doi: 10.1038/s41398-019-0486-6

Table 4.

Demographic and clinical characteristics of the marker-positive subgroup of cohort II

No marker combination (n = 37) Marker combination (n = 13) F(df1, df2) P
M (SD) M (SD)
Age 32.24 (11.13) 40 (11.19) 4.66 (1, 48) 0.036*
Duration of illness 8.55 (9.04) 9.54 (8.33) 0.12 (1, 48) 0.732
Hospitalizations 4.03 (3.33) 3.15 (1.57) 1.54 (1, 43.31) 0.222
PANSS total 61.67 (17.50) 54.92 (12.44) 1.62 (1, 47) 0.209
PANSS positive 14.03 (5.59) 11.54 (3.57) 2.23 (1, 47) 0.142
PANSS negative 16.75 (5.12) 16.69 (6.58) <0.01 (1, 47) 0.125
PANSS general 30.89 (9.31) 26.69 (4.11) 4.75 (1, 44.86) 0.035*
No marker combination (n = 37) Marker combination (n = 13)
Mdn Mdn U P
CPZ 467.86 467.5 253.5 0.773
Age of onset 21 30 331 0.045*
Educational years 13 16 321.5 0.072
No marker combination (n = 37) Marker combination (n = 13) χ2(df1) P
Sex (male:female) 29:9 8:2 0.45 (1) 0.503
Clozapine users (yes:no) 5:32 8:5 3.74 (1) 0.053
Language (German:foreign) 30:7 13:0 2.86 (1) 0.091
Handedness (right:left:both) 33:4:0 11:1:1 2.96 (2) 0.227

CPZ chlorpromazine equivalents (cross-sectional at day of blood drawing), PANSS positive and negative syndrome scale, M mean, SD standard deviation, Mdn median, df degree of freedom, F F statistic, U Mann–Whitney-U, P p-value

Statistics represent the comparison of the patient groups with and without the marker combination