Karnik 1992.

Methods	Non‐random
Participants	104: 14 underwent EC/IC bypass, 14 received best medical treatment Blood flow velocity measurement was assessed in 6 patients with EC/IC bypass surgery and in 4 controls
Interventions	EC/IC bypass
Outcomes	Death from all causes, any stroke during follow up, improvement of vasomotor reactivity in patients with EC/IC bypass after acetazolamide application
Notes	Randomisation procedure not described in detail
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ Adequate