Harada 1991B(2).

Study characteristics
Methods	Unit of randomisation: child Method of randomisation: centralised randomisation Timing of randomisation: at diagnosis Blinding: unclear Power calculation: nil Number of centres: not stated. However the paper states "multicentre" 295 patients randomised in all 3 comparisons 6 exclusions at 30 days, 17 at 60 days and 18 at 1 year 289 patients analysed at 30 days, 278 at 60 days and 277 at a year Source of funding: not stated
Participants	Children within 7 days of the onset of symptoms. Diagnostic criteria not stated Age: under 4 years Location: Japan Timing and duration: 1985‐1986
Interventions	100 mg/kg/day pepsin‐treated IVIG + 50 mg/kg/day oral aspirin Control: 50 mg/kg/day oral aspirin Duration: 5 days (IVIG), aspirin duration not stated
Outcomes	Coronay artery abnormalities
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate