Ogino 1987B.

Study characteristics
Methods	Unit of randomisation: child Method of randomisation: centrally randomised Timing of randomisation: at diagnosis Blinding: not stated. Clearly the patients and the treatment providers were not blinded. It is not stated if outcome assessors had any blinding Power calculation: nil Number of centres: 32 142 patients randomised 25 exclusions 117 patients analysed Source of funding: not stated
Participants	Children within 7 days of onset of illness. Diagnostic criteria were not defined. Children who had received any IVIG prior to randomisation were excluded Age: not stated. Untl at least 72 months Location: Japan Timing and duration: 1985‐1986
Interventions	400mg/kg/day of S‐Sulphonated IVIG + 30/mg/kg/day of aspirin until serum CPR became negative and then 10/mg/kg/day Control: yes (aspirin only) Duration: 3 days (IVIG), aspirin duration not stated
Outcomes	Coronary artery aneurysms Coronary artery dilations
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	A ‐ Adequate