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. 2013 Jul 30;2013(7):CD007410. doi: 10.1002/14651858.CD007410.pub2

Comparison 1. Acupuncture versus sham acupuncture.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Hot flush frequency (number/day) 8 414 Mean Difference (IV, Random, 95% CI) ‐1.13 [‐2.55, 0.29]
1.1 Traditional vs. sham acupuncture 6 332 Mean Difference (IV, Random, 95% CI) ‐1.65 [‐3.62, 0.32]
1.2 Electroacupuncture vs. sham acupuncture 1 28 Mean Difference (IV, Random, 95% CI) ‐0.30 [‐3.60, 3.00]
1.3 Changes in frequency of hot flushes from baseline to end of study 1 54 Mean Difference (IV, Random, 95% CI) ‐0.20 [‐1.68, 1.28]
2 Hot flush severity 6 297 Std. Mean Difference (IV, Random, 95% CI) ‐0.45 [‐0.84, ‐0.05]
2.1 Traditional vs. sham acupuncture 4 215 Std. Mean Difference (IV, Random, 95% CI) ‐0.44 [‐0.98, 0.10]
2.2 Electroacupuncture vs. sham acupuncture 1 28 Std. Mean Difference (IV, Random, 95% CI) ‐0.09 [‐0.83, 0.66]
2.3 Changes in severity of hot flushes from baseline to end of study 1 54 Std. Mean Difference (IV, Random, 95% CI) ‐0.77 [‐1.33, ‐0.22]
3 Hot flush frequency in trials less than 12 weeks 6 335 Mean Difference (IV, Random, 95% CI) ‐1.68 [‐3.61, 0.24]
3.1 Traditional vs. sham acupuncture 5 281 Mean Difference (IV, Random, 95% CI) ‐2.29 [‐4.88, 0.31]
3.2 Changes in frequency of hot flushes from baseline to end of study 1 54 Mean Difference (IV, Random, 95% CI) ‐0.20 [‐1.68, 1.28]
4 Hot flush frequency in trials of 12 weeks and more 3 103 Mean Difference (IV, Random, 95% CI) 0.15 [‐1.11, 1.40]
4.1 Traditional vs. sham acupuncture 1 51 Mean Difference (IV, Random, 95% CI) 0.10 [‐1.47, 1.67]
4.2 Electroacupuncture vs. sham acupuncture 1 28 Mean Difference (IV, Random, 95% CI) ‐0.30 [‐3.60, 3.00]
4.3 Changes in frequency of hot flushes from baseline to end of study 1 24 Mean Difference (IV, Random, 95% CI) 0.60 [‐2.13, 3.33]
5 Hot flush frequency in cancer trials 2 126 Mean Difference (IV, Random, 95% CI) ‐6.20 [‐16.03, 3.64]
5.1 Traditional vs. sham acupuncture 2 126 Mean Difference (IV, Random, 95% CI) ‐6.20 [‐16.03, 3.64]
6 Hot flush severity in cancer trials 1 60 Mean Difference (IV, Fixed, 95% CI) ‐2.40 [‐3.50, ‐1.30]
7 Hot flush severity in trials less than 12 weeks 5 269 Std. Mean Difference (IV, Random, 95% CI) ‐0.50 [‐0.95, ‐0.06]
7.1 Traditional vs. sham acupuncture 4 215 Std. Mean Difference (IV, Random, 95% CI) ‐0.44 [‐0.98, 0.10]
7.2 Changes in severity of hot flushes from baseline to end of study 1 54 Std. Mean Difference (IV, Random, 95% CI) ‐0.77 [‐1.33, ‐0.22]
8 Hot flush severity in trials of 12 weeks and more 2 52 Std. Mean Difference (IV, Random, 95% CI) ‐0.09 [‐0.63, 0.46]
8.1 Electroacupuncture vs. sham acupuncture 1 28 Std. Mean Difference (IV, Random, 95% CI) ‐0.09 [‐0.83, 0.66]
8.2 Changes in severity of hot flushes from baseline to end of study 1 24 Std. Mean Difference (IV, Random, 95% CI) ‐0.09 [‐0.89, 0.72]
9 Quality of life 3 104 Std. Mean Difference (IV, Random, 95% CI) 0.12 [‐0.26, 0.51]
9.1 Traditional vs. sham acupuncture 2 80 Std. Mean Difference (IV, Random, 95% CI) 0.11 [‐0.33, 0.55]
9.2 Changes in quality of life from baseline to end of study 1 24 Std. Mean Difference (IV, Random, 95% CI) 0.16 [‐0.64, 0.96]
10 Quality of life in trials less than 12 weeks 1 29 Std. Mean Difference (IV, Random, 95% CI) 0.13 [‐0.61, 0.87]
10.1 Traditional vs. sham acupuncture 1 29 Std. Mean Difference (IV, Random, 95% CI) 0.13 [‐0.61, 0.87]
11 Quality of life in trials of 12 weeks and more 1 51 Std. Mean Difference (IV, Random, 95% CI) 0.10 [‐0.45, 0.66]
11.1 Traditional acupuncture vs. sham acupuncture 1 51 Std. Mean Difference (IV, Random, 95% CI) 0.10 [‐0.45, 0.66]