FIG 3.

E. coli MG1655 was associated with the pathogenesis of ANP. (A and B) Quantity of E. coli (species) (A) and E. coli MG1655 (strain) (B) as determined by qPCR in normal controls (NC) and AP patients. (C and D) Quantity of E. coli (species) (C) and E. coli MG1655 (strain) (D) as determined by qPCR in SO and ANP rats. (E) Correlation analysis of E. coli MG1655 and IL-17A and IL-1β in the intestine, DAO and d-lactate in the plasma, and ileal histopathological scores as determined by using a Spearman test. n = 10 per group. Three independent experiments were performed. Comparison between two groups (NC versus AP and SO versus ANP) was performed by Student t test, and the correlation between E. coli MG1655 and indicators of intestinal injury was analyzed by using a Spearman test. *, P < 0.05 versus the NC or SO group. SO, sham operated.