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. 2019 Apr 10;294(21):8577–8591. doi: 10.1074/jbc.RA118.006871

Figure 3.

Figure 3.

Characterization of adipose-specific EZH2 KO mice. Adipoq-Cre+/EZH2f/f and EZH2f/f littermate control mice were fed a standard chow diet for 34 weeks (n = 4–6). A, body weights and representative gross morphology of 34-week-old mice. B, whole-body fat and lean composition by noninvasive NMR. C, average food intake and locomotor activity over 72 h monitored via CLAMS. D and E, representative plasma lipoprotein profile measured via FPLC using pooled plasma (0.22 ml) from three Adipoq-Cre+/EZH2f/f mice and six EZH2f/f mice. Total plasma (F) triglyceride and cholesterol levels (G). *, p < 0.05. Adipoq, adiponectin; VLDL, very low-density lipoprotein; IDL, intermediate-density lipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein. Error bars, S.E.