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. 2019 Apr 10;294(21):8577–8591. doi: 10.1074/jbc.RA118.006871

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© 2019 Yiew et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 6. — Effects of EZH2 inhibition on lipoprotein uptake and ApoE expression in adipocytes. A, intracellular triglyceride levels in adipocytes cultured with lipoprotein-deficient medium. Fluorescent Dil-VLDL internalization was measured in human (B) and mouse adipocytes (C) treated with GSK126 or vehicle. Shown is ApoE mRNA expression in human (D) and mouse adipocytes (E) treated with GSK126 or vehicle. F, fluorescent Dil-VLDL internalization in WT and ApoE-deficient adipocytes treated with GSK126 or vehicle. *, p < 0.05; **, p < 0.01; LD, lipoprotein-deficient. Error bars, S.E.